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Editor-in-Chief         

EB Itzik HAROSH

 

 

 

 

Dr. Itzik Harosh
ObeTherapy Biotechnology, France



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      metallodrugs 12      

Systems Biology of the Proteomic Analysis of Cytotoxic Gold Compounds in A2780 Ovarian Cancer Cell Line: A Network Analysis

Gold and ruthenium compounds hold today great promise as new metallodrugs for treatment of human ovarian carcinoma; yet, their mode of action is still largely unknown. To shed light on their molecular mechanisms in previous studies we performed proteomic analysis in the A2780 human ovarian cancer cell line, after treatment with four different gold and two ruthenium compounds.

      aromatic cluster 21  

Two Hypothetical Proteins from Bacillus thuringiensis Genomes were Parasporinlike Proteins

Parasporins are a group of anti-cancer proteins from Bacillus thuringiensis that preferentially kill cancer cells leaving the normal cells unaffected. Two hypothetical proteins were found from B. thuringiensis genomes to be homologous to Parasporin-2. Their structures were both β-sheet-dominant one with 4 α-helix occurred only in domain I, which were also seen in Parasporin-2. 2.

Journal Highlights

  • Computation biology
  • Genomics
  • Evolutionary bioinformatics
  • Bioinformatics and biostatistics
  • Proteomics and Secretomics
  • Proteogenomics
  • Interaction proteomics
  • Emerging trends and Current Proteomic Technologies
  • Comparative genomics
  • Bioinformatics and management systems
  • Computational bio modelling
  • Health informatics
  • Bioinformatics software and development
  • Bioinformatics and Phylogenetic
  • Bioengineering
  • Mathematical and theoretical biology
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